DanStem Seminar by Raphael Kopan – University of Copenhagen

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DanStem Seminar by Raphael Kopan

April 4, 2018, Raphael Kopan, Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Ohio 
Title: TBA

The Kopan laboratory is interested in mechanisms of Notch signaling, organogenesis, and disease processes. Their mechanistic interests are now focused on Notch activity in the nucleus; they are developing new tools to understand Notch concentration-dependent gene regulation. the group investigations explain why Alagille syndrome patients have renal malformations and may lead to a treatment strategy. Because many cell types are born from groups of equivalent precursors, Notch is involved in many steps during kidney development, several of which are not yet fully explored.