19 June 2015
Third prize to Maya Friis Kjærgaard's presentation
Maya Friis Kjærgaard, a PhD student from the Semb lab has won the 3rd best speaker award for her presentation at the MoMed summer school 2015, Pharmakon Conference Centre in Hillerød.
Maya gave an enthusiastic 15 minute talk about her research project, which is about: iPSC disease modeling of monogenic forms of diabetes.
'Perturbation of pancreatic beta-cell function is generally regarded as the cause of type 2 diabetes (T2D), however, the exact mechanism behind these perturbations is not yet fully understood. In this project, we aim to establish in vitro models of monogenic hereditary forms of beta-cell dysfunction using iPSC lines from donors with Maturity Onset Diabetes of the Young 3 (MODY3). Isogenic control iPSC lines will be generated using CRISPR technology to correct the inherited mutations present in the MODY3 iPSC lines. By differentiating MODY3 iPSCs as well as the corrected isogenic controls into beta cells, we hope to establish a model system that can be used to investigate the underlying molecular mechanisms causing the disease'.