14 November 2014
Making insulin producing beta cells from stem cells - how close are we?
Professor Semb comments on two recent studies that revealed for the first time how to generate insulin producing cells, which resemble normal beta cells in the lab from human pluripotent stem cells
Although remarkable progress has been made during the past decade it was not until recently that scientists (the Kieffer/BetaLogics team in September and the Melton lab in October) were able to make insulin-producing cells from hPSCs that share significant functional features with normal human beta cells.
But how alike are these cells to the beta cells found in our bodies? How close are we to testing these cells in diabetics? And what other questions still remain? In this commentary, Henrik Semb tackles these questions providing perspective in this complex and challenging field.
Image: The unseen world, Insulin-producing cells made from human embryonic stem cells
Link to the article: http://www.eurostemcell.org/commentanalysis/making-insulin-producing-beta-cells-stem-cells-how-close-are-we
This commentary was created by Henrik Semb and was reviewed and contributed to by Olle Korsgren and Jacqueline Ameri with editing by Cathy Southworth