13 August 2015
DanStem Seminar by Olov Andersson, August 26, 2015
Olov Andersson, Karolinska Institute. Title: Accelerating β-cell regeneration by high-throughput screening in zebrafish
Olov Andersson's group is currently focusing on pancreatic beta-cell regeneration. Increasing the number of insulin-producing beta-cells might prove a better treatment for diabetes, which is at present controlled but not cured by insulin injections.
Diabetes is characterized by elevated blood glucose levels, a consequence of insufficient insulin supply and/or insulin resistance. Despite mechanistic differences, both type 1 and late-stage type 2 diabetes feature depletion of beta-cells.
Experimental ablation of beta-cells by chemical treatment or partial pancreatectomy in zebrafish and rodents is followed by significant recovery of the beta-cell mass, indicating that the pancreas has the capacity to regenerate. This regenerative capacity could potentially be exploited therapeutically - if the underlying mechanisms were better understood.
Time: 26 August 2015, 12:00
Place: CPR Seminar room Panum Building 6, 2nd floor
To find out more about DanStem seminars, please see our seminars' plan for 2015
All are welcome. Registration is not needed.