22 September 2015
DanStem Seminar by Tristan Rodriguez, September 30, 2015
Tristan Rodriguez, Imperial College, London Title: Cell competition: A mechanism to ensure metabolic fitness during differentiation?
The research of the Rodriguez lab focuses on understanding the mechanisms that control cell fate decisions and cell survival in the early mammalian embryo. The main models used for these studies are genetically manipulated embryos and embryonic stem cells. Specifically, the Rodriguez group studies how cells exit the pluripotent state and initiate the differentiation program to form the three definitive germ layers that will give rise to the precursors of all the tissues and organs of the fetus: the endoderm, mesoderm and ectoderm.
This research involves analysing the signalling pathways, transcriptional events, cellular metabolic pathways and epigenetic mechanisms that regulate germ layer differentiation. By integrating this information into the context of the developing embryo they hope to achieve an understanding of how multiple cellular and molecular inputs are coordinated during the differentiation process and to apply the knowledge we obtain to regenerative medicine.
30 September 2015, 12:00
CPR Seminar room Panum Building 6, 2nd floor
All are welcome. Registration is not needed.