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DanStem Newsletter December 2015
The Novo Nordisk Foundation enables the development of new research lines at DanStem
DanStem receives the donation based on an application for New Strategic Funding of the Novo Nordisk section of Basic Stem Cell Biology.
To promote Copenhagen as an international beacon of research within biomedicine and biotechnology, The Novo Nordisk Foundation has awarded an additional grant of DKK 235 million (€31.4 million) to DanStem to develop the activities of the center, especially in the fields of cancer stem cells and bioengineering.
“This grant will enable us to continue to position the center internationally as a leader in basic and translational stem cell research in the diabetes and cancer areas,” says Professor Henrik Semb, Executive Director of DanStem. Read more HERE
Grand opening of the core zebrafish facility
Joint Lund-Copenhagen Stem Cell Center Symposium
Copenhagen Stem Cell, Development & Differentiation Club
The Stem Cell Club had its third meeting on October 19, 2015.
Postdoctoral Fellow Robert Bone from DanStem, The Brickman group recieved DKK 2,107,103 from the Danish Council for Independent Research for his project: Investigating the Role of Lipid Metabolism in Early Embryonic Development. He joined Joshua Brickman’s laboratory at DanStem in 2014 and is carrying out his research project in collaboration with the Novo Nordisk Foundation Center for Metabolic Research.
DanStem has received a Lundbeck Foundation grant to cover all costs of organizing dissemination and outreach activities in the coming three years. This initiative was managed by Assistant Professor Mette Jørgensen and Research Coordinator Simone Wenkel, you can read more about it HERE.
Laura Martin Coll from the Grapin-Botton group received a Novo Scholarship Grant from Novo Nordisk to do her Master's thesis at DanStem.
Sara Caviglia from the Ober group will receive an ‘Early Postdoc.Mobility’ Fellowship from the Swiss National Research Foundation.
Florian Malte Hermann from the Semb group has received a third PhD scholarship from the Danish Diabetes Academy
Porse group (2015). The multifaceted functions of C/EBP[alpha] in normal and malignant hematopoiesis. Leukemia,doi:10.1038/leu.2015.324.
Helin group (2015). SWI/SNF Subunits SMARCA4, SMARCD2 and DPF2 Collaborate in MLL-Rearranged Leukaemia Maintenance.Plos One, 10(11), e0142806, doi:10.1371/journal.pone.0142806.
Grapin-Botton group (2015). Longitudinal three-dimensional visualisation of autoimmune diabetes by functional optical coherence imaging. Diabetologia, 1-10, doi:10.1007/s00125-015-3819-x.
Helin group (2015). H3K23me2 is a new heterochromatic mark in Caenorhabditis elegans. Nucleic Acids Res, doi:10.1093/nar/gkv1063.
Ole William Petersen group (2015). Propagation of oestrogen receptor-positive and oestrogen-responsive normal human breast cells in culture. Nature Communications, 6, doi:10.1038/ncomms9786.
Helin group (2015). Tumor suppressor ASXL1 is essential for the activation of INK4B expression in response to oncogene activity and anti-proliferative signals. Cell Res, doi:10.1038/cr.2015.121.
Kassem group (2015). Association between in vivo bone formation and ex vivo migratory capacity of human bone marrow stromal cells. Stem Cell Res Ther, 6196, doi:10.1186/s13287-015-0188-9.
Serup group (2015). A Gene Regulatory Network Cooperatively Controlled by Pdx1 and Sox9 Governs Lineage Allocation of Foregut Progenitor Cells. Cell Reports, doi: 10.1016/j.celrep.2015.08.082.
Porse group (2015). ERG promotes the maintenance of hematopoietic stem cells by restricting their differentiation. Genes & Development, 29(18), 1915-1929, doi:10.1101/gad.268409.115.
Brickman group (2015). LIF supports primitive endoderm expansion during pre-implantation development. Development, doi:10.1242/dev.125021.
Porse group (2015). Disease evolution and outcomes in familial AML with germline CEBPA mutations. Blood, 126(10), 1214-1223, doi:10.1182/blood-2015-05-647172.
Kassem group (2015). CDH1 and IL1-beta expression dictates FAK and MAPKK-dependent cross-talk between cancer cells and human mesenchymal stem cells. Stem Cell Res Ther, 6(1), 135, doi:10.1186/s13287-015-0123-0.
Kassem group (2015). Inhibiting actin depolymerization enhances osteoblast differentiation and bone formation in human stromal stem cells. Stem Cell Res, 15(2), 281-289, doi:10.1016/j.scr.2015.06.009.
Grapin-Botton group (2015). REST represses a subset of the pancreatic endocrine differentiation program. Developmental Biology, doi:10.1016/j.ydbio.2015.07.002. (epub ahead of print).
DanStem PhD Course 2015 on Signalling in Embryonic Development and Stem Cells
DanStem offers an annual PhD course, organized together with The Danish Research Programme on Molecular Mechanisms of Disease, (MoMeD). This year we offered a combination of a practical/theoretical course, with hands on experience. The course was organized by Professor Palle Serup and Associate Professor Elke Ober from DanStem. Three international guest speakers were invited and gave double lectures each, where all at the faculty were invited. 12 students have participated in the course.
Copenhagen Bioscience PhD programme
The Copenhagen Bioscience PhD programme is a new initiative that offers talented students with a university degree from outside of Denmark an opportunity to launch their careers in the vibrant environment of the Novo Nordisk Foundation research centre cluster. Four PhD students will join DanStem annually, starting 2016. To read more about this initiative, please follow this LINK
Interview with DanStem Executive Director, Professor Henrik Semb
Stem Cell Research – the big challenge
Sund Campaign : Sundere SUND kampagnen
DanStem Professor Joshua Brickman took part in the faculty's latest campaign on the topic: How to make the Faculty of Health Healthier. All the videos of the campaign are published on Instagram, where you can find the video of Joshua, among all other videos of the faculty
Interview with DanStem Professor Kristian Helin
Public Health Students visit DanStem
Ca-Op, Career and funding opportunities for young scientists
Hosting a Gymnasium Student
DanStem New Head of Administration
Sendt d. 11 December 2015