DanStem Seminar by Kate Storey
Kate Storey, School of Life Sciences, University of Dundee
Title: Mechanisms regulating neural differentiation
The Storey group wishes to understand how neural cells arise and how their proliferation and differentiation are controlled. Their work focuses on the developing spinal cord and insights from these studies inform investigation of these processes in embryonic stem cell derived neural tissue and in maturing spinal cord progenitors, which become adult neural stem cells. The group addresses these questions using cell specific gain and loss of gene function approaches as well as genome-wide analyses and real-time imaging techniques. The overall aim of the work is to identify the gene regulatory mechanisms that control neural differentiation, with a long-term goal to inform strategies for therapeutic treatment of neural injury and disease.