15 September 2020

DanStem Seminar by Tariq Enver

seminar

September 23rd at 16:15. Niels K. Jerne Auditorium and online 

Professor Tariq Enver, University College London

 Talk title: 'Origin, evolution and therapy resistance in childhood leukaemia'

 September 23rd at 16:15. Niels K. Jerne Auditorium and online 

 Zoom link: https://ucph-ku.zoom.us/j/68901681474

Because of their unique biological properties and potential medical importance, stem cells have attracted major scientific, commercial and public interest (Weissman et al, Annu Rev Cell Dev Biol; 17:387-403, 2001). The cell fate options that confront stem cells include self-renewal, differentiation and lineage-specification, programmed cell death and quiescence. Within haematopoiesis, constitutive dysregulation of the balance between these processes is an essential feature of leukaemogenesis. A key challenge is to understand how the different cell fates that confront stem and progenitor cells are selected and co-ordinated; adoption of a given fate must be coupled to appropriate suppression of alternative fates.

Read more about Professor Enver's research