The candidate is expected to work on the engineering of human pluripotent stem cell-derived islet of Langerhans-like aggregates with functional properties close to human islets. The functionality and therapeutic potential of the aggregates will be tested in vitro and in vivo in mice.
The goal of this project is to engineer therapeutically active islet-like aggregates for future cell therapy phase 1 trials in Type 1 Diabetes (T1D).
The candidate is expected to use state-of-the-art genetics, molecular and cell biological, and tissue engineering experimental strategies. The candidate will work together with a dedicated team of scientists and technicians who together will tackle bottle-necks towards implementing the phase 1 clinical trials in T1D.
The candidate is required to hold a PhD degree in pluripotent stem cell/developmental biology. A few years of postdoctoral experience in the same areas is a merit. The candidate should also have hands on experience in human pluripotent stem cell maintenance and differentiation, 3D culture of pluripotent stem cells, various cell and molecular biological methods, flow cytometry and live-cell imaging. Experience in differentiation towards pancreatic lineages is a merit. Finally, we are looking for applicants with a good record of peer reviewed scientific publications, grant writing skills and an interest in team work.
About our center:
The Novo Nordisk Foundation Center for Stem Cell Biology – DanStem – addresses basic research questions in stem cell and developmental biology and translates results from basic research into new strategies and targets for the development of new therapies for diabetes and cancer. DanStem was established as a result of a series of international recruitments coupled with internationally recognized research groups focused on insulin producing beta cells and cancer research already located at the University of Copenhagen.
The position is for 2 years with a possible extension. The employment is planned to start as soon as possible or upon agreement.
The terms of employment are set according to the Agreement between the Ministry of Finance and The Danish Confederation of Professional Associations or other relevant professional organization. The position will be at the level of postdoctoral fellow and the basic salary according to seniority is 32.700-34.400 DKK/month. A supplement could be negotiated, dependent on the candidate´s experiences and qualifications. In addition, a monthly contribution of 17.1% of the salary is paid into a pension fund.
Applicants recruited from abroad may be eligible for a special researcher taxation scheme. In all cases, the ability to perform the job will be the primary consideration, and thus we encourage all - regardless of their personal background and status - to apply.
The application must be submitted online and in English, by clicking on “Apply online” below.
The closing date for applications is July 15th 2018 at 23.59pm.
The application must include:
- Cover letter detailing the basis on which the applicant scientific qualifications meet the requirements for this position.
- Curriculum vitae.
- List of references (full address, incl. email and phone number)
- Diplomas – all relevant certificates.
- List of publications.
The further process:
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the Appointments Committee. All applicants are then immediately notified whether their application has been passed for assessment by an expert assessment committee. Selected applicants are notified of the composition of the committee and each applicant has the opportunity to comment on his/her assessment. You may read about the recruitment process on
DanStem and The University of Copenhagen wish to reflect the diversity of society and welcome applications from all qualified candidates, regardless of personal background