DanStem Newsletters – University of Copenhagen

DanStem > DanStem Newsletter

DanStem Newsletter January 2015

DanStem Newsletter, January 2015

The Danish Stem Cell Center of excellence, DanStem, was established as an initiative of The Novo Nordisk Foundation

DanStem National Collaborative Initiative

In the summer of 2014, DanStem invited Danish researchers and research groups to submit proposals for national collaborative projects. Three projects were funded and will commence in 2015. The national collaborative initiative is supported by a donation from the Novo Nordisk Foundation, aiming to strengthen and develop basic research within the areas of stem cells and developmental biology in Denmark.

The following collaborative projects will be launched in 2015:
  • Ribo-regulation in stem cell differentiation
Coordinated by: Torben Heick Jensen, Department of Molecular Biology and Genetics, University of Aarhus, and Kristian Helin, The Danish Stem Cell Center (DanStem), the University of Copenhagen
  • Comparing stem cell-based mechanisms of liver and heart regeneration
Coordinated by: Ditte Caroline Andersen, Department of Clinical Biochemistry and Pharmacology, Laboratory of Molecular and Cellular Cardiology, Odense University Hospital/Clinical Institute, University of Southern Denmark, and Elke Ober, The Danish Stem Cell Center (DanStem), the University of Copenhagen
  • Control of stem cell fate by (epi)genomic editing of enhancers
Coordinated by: Susanne Mandrup, Department of Biochemistry and Molecular Biology, University of Southern Denmark, and Bo Porse, The Danish Stem Cell Center (DanStem), the University of Copenhagen.

DanStem Seminars 2015

The DanStem Seminar Series focuses on topics within stem cell and developmental biology. It features internationally renowned scientists and it is organized and coordinated by DanStem's Principal Investigator, Professor Anne Grapin-Botton. In 2014 DanStem hosted 18 top researchers. The seminar speakers met with DanStem scientists as well as interested scientists from the University of Copenhagen. 

Most seminars take place on Wednesdays, starting at 12:00 at The Panum Institute, Building 6, 2nd floor, The Novo Nordisk Foundation Center for Protein Research, Seminar room (Map). The seminar plan for 2015 is available here: https://danstem.ku.dk/news/seminars-2015/     
The DanStem seminars are open to all; registration is not needed. 


DanStem Principle Investigators are training 38 Post-Doctoral students, 26 PhD students, 3 Pre-Doctoral students, and 10 Masters students.  

DanStem has recently developed a Strategy for Education, where our vision, actions and plans for the future are stated. You can read the document HERE.

DanStem PhD course 2014: Lecture by Prof. Benvenisty, from the Hebrew University of Jerusalem


DanStem scientists have contributed to more than 45 publications during 2014. An example of a recent publication is the following: 

The Brickman group has gained new insight into embryonic stem cells and how blocking their ability to make choices explains why they remain stem cells in culture. The results have been published in the scientific journal Cell Reports. This latest research by Prof. Joshua Brickman and his research team found that inhibiting or blocking the ability of stem cells to make a specific decision leads to better cell growth, and could lead to defined ways to differentiate stem cells. 

Link to the paper: 
Hamilton, William B. & Joshua M. Brickman (2014). Erk Signaling Suppresses Embryonic Stem Cell Self-Renewal to Specify Endoderm. Cell Reports, 9(6), 2056-2070, doi:10.1016/j.celrep.2014.11.032.

To find out more about our publications, please see: https://danstem.ku.dk/research1/publications/  

Dissemination and outreach

  • Interview with Professor Henrik Semb about the pancreas, beta cells and Diabetes 

In this interview, DanStem Director, Professor Henrik Semb, describes his career track and his current research. He talks about his interest in Diabetes stem cell research and gives his advice to young scientists. You can read the full interview via this link: http://www.eurostemcell.org/commentanalysis/interview-henrik-semb-pancreas-beta-cells-and-diabetes   

  • Special seminar about dissemination and outreach 

Dr Cathy Southworth from the Centre for Regenerative Medicine, The University of Edinburgh, has visited DanStem on November 5, 2014 for a seminar on Outreach and Public Engagement. During this session the attendees could explore some of the tools available to support public engagement, and feel more confident regarding how to talk about their research to non-specialists.

  • Making insulin producing beta cells from stem cells - how close are we? 

Professor Henrik Semb, DanStem Director, has commented on two recent studies that revealed for the first time how to generate insulin-producing cells, which resemble normal beta cells in the lab from human pluripotent stem cells. You can read the full commentary HERE.

Learning about stem cells via a game, outreach and dissemination seminar with Cathy Southworth

Upcoming stem cell events

Symposium on "Stem Cells in Tissue Re-generation and Cancer" hosted by The Royal Danish Academy of Scieneces and Letters, April 16, 2015, H.C. Andersens Boulevard 35, DK-1553 København V. Organizers: Kristian Helin and Jiri Bartek.

You can find more information about stem cell related events HERE

Follow our website and learn more about our activities: https://danstem.ku.dk/ 

To reply to this email, please write to naomi.dayan@sund.ku.dk


Sendt d. 30 January 2015