Elisabetta Ferretti

Associate Professor of Developmental Biology


Research profile

The goal of Elisabetta Ferretti and her group is to establish how transcription factors (TF) and signaling pathways interact to define a precise cell fate. Altered transcriptional programs are a hallmark of developmental malformations and diseases such as cancer. Thus, unraveling complex transcriptional networks in the embryo or in cellular systems will help understanding of how diseases occur and, in the long run, provide strategies for prevention and cure.

Awards and Honours

2015 Project1 grant from The Danish Council for Independent Research (Styrelsen for Forskning og Innovation Grant) 

2015 Marie Curie Individual Fellowship – Re-Integration panel

2005 Marie Curie Outgoing International Fellowship.

2002 EMBO Short-Term Fellowship.

2001 First Prize “ Outstanding Young Researcher 2001” DIBIT, Milan.

1998 EMBO Short-Term Fellowship

Research Profile

Since 2013, Associate Professor, junior group leader at Novo Nordisk Foundation Center for Stem Cell Biology, DanStem, University of Copenhagen

2010-2013 Senior Research Associate, Laboratory of Dr. Licia Selleri, Department of Cell and Developmental Biology, Supervisor of two PhD students and two postdocs Weill Medical College of Cornell University, New York, USA.

2004-2010, Postdoctoral Fellow, Laboratory of Dr. Licia Selleri, Department of Cell and Developmental Biology, Weill Medical College of Cornell University, New York, USA.

2007, Visiting Postdoctoral Fellow, Laboratory of Dr. Filippo Rijli, Department of Developmental Biology, Institut de Genetique et de Biologie Moleculaire et Cellulaire (IGBMC), Strasbourg, France.

2004, Ph.D. in Molecular Biology, Open University, London, PhD thesis defense,University Vita Salute, San Raffaele Hospital, Milan, Italy.

Selected Publications

Golonzhka, O., Nord, A., Tang, P.L.F., Lindtner, S., Ypsilanti, A.R., Ferretti, E., Visel, A., Selleri, L. and Rubenstein, J.L.R. (2015). Pbx Regulates Patterning of the Cerebral Cortex in Progenitors and Postmitotic Neurons. Neuron 88, 1192-1207, doi:10.1016/j.neuron.2015.10.045.

Handschuh, K., Feenstra, J., Koss, M., Ferretti, E., Risolino, M., Zewdu, R., Sahai, M.A., Bénazet, J.D., Peng, X.P., Depew, M.J., Quintana, L., Sharpe, J., Wang, B., Alcorn, H., Rivi, R., Butcher, S., Manak, J.R., Vaccari, T.,  Weinstein, H., Anderson, K.K., Lacy, E., and Selleri, L. (2014). ESCRT-II/Vps25 constrains digit number by endosome-mediated selective modulation of FGF-SHH signaling. Cell Reports 9, 674-87, doi: 10.1016/j.celrep.2014.09.019.

Feldhahn, N., Ferretti, E., Robbiani, D., Callen, E., Deroubaix, S., Selleri, L., Nussenzweig, A., and Nussenzweig, M.C. (2012). The hSSB1 orthologue Obfc2b is essential for skeletogenesis but dispensable for the DNA damage response in vivo. EMBO Journal 31, 4045-4056, doi: 10.1038/emboj.2012.247.

Sgado, P., Ferretti, E., Grbec, D., Bozzi, Y., and Simon, H.H. (2012).The atypical homeoprotein Pbx1a participates in the axonal pathfinding of mesencephalic dopaminergic neurons. Neural Development 7, doi:10.1186/1749-8104-7-24.

Ferretti, E., Li, B., Zewdu, R., Wells, V., Hebert, J.M., Karner, C., Anderson, M.J., Williams, T., Dixon, J., Dixon, M.J., Depew, M.J., and Selleri, L. (2011). A Conserved Pbx-Wnt-p63-Irf6 Regulatory Module Controls Face Morphogenesis by Promoting Epithelial Apoptosis. Developmental Cell 21, 627-641, doi:10.1016/j.devcel.2011.08.005. (Highlight on the “Faculty of 1000” and “Science” magazine in their “Editor’s Choice” editorial (issue of 28 October 2011).

Vitobello, A.*, Ferretti*, E., Lampe, X., Vilain, N., Ducret, S., Ori, M., Spetz, J., Selleri, L., and Rijli, F.M. (2011). Hox and Pbx Factors Control Retinoic Acid Synthesis during Hindbrain Segmentation. Developmental Cell, 20, 469-482, doi: 10.1016/j.devcel.2011.03.011. *authors contributed equally.