Pancreas Development and Pancreatic Cancer

Arnes Group

The Arnes group investigates how molecular determinants of cellular identity, with a particular focus in non-coding RNAs, regulate the initiation and progression of pancreatic cancer.

The group is interested in understanding how long non-coding RNAs interact with transcription factors and chromatin modifiers to regulate gene expression and cellular plasticity in development and disease. The long-term goal is to devise cancer therapies based in altering the activity of transcriptional regulators of pancreas differentiation.