List of publications

Filimonow, K., Saizz, N., Suwiska, A., Wyszomirski, T., Grabarek, J.B., Ferretti, E., Piliszek, A., Plusa, B., and Maleszewski, M. (2019). No evidence of involvement of E-cadherin in cell fate specification or the segregation of Epi and PrE in mouse blastocysts. PLoS One 14:e0212109. doi: 10.1371/journal.pone.0212109

Ferretti, E., Hadjantonakis, A.-K. (2019). Mesoderm specification and diversification: from single cells to emergent tissues. Current Opinions in Cell Biology, 61, 110-116, doi: 10.1016/

Selleri, L., Zappavigna, V., Ferretti, E. (2019). 'Building a perfect body': control of vertebrate organogenesis by PBX-dependent regulatory networksGenes & Development, 33, 258-275, doi: 10.1101/gad.318774.118.

Welsh, I.C., Hart, J., Brown, J.M., Hansen, K., Marques, M.R., Aho, R.J., Grishina, I., Hurtado, R., Herzlinger, D., Ferretti, E., Garcia‐Garcia, M.J. and Selleri, L. (2018). Pbx loss in cranial neural crest, unlike in epithelium, results in cleft palate only and a broader midface. Journal of Anatomy 233, 222-242, doi: 10.1111/joa.12821.

Losa, M., Risolino, M., Li, B., Hart, J., Quintana, L., Grishina, I., Yang, H., Choi, I.F., Lewicki, P., Khan, S., Aho, R., Feenstra, J., Vincent, C.T., Brown, A.M.C., Ferretti, E., Williams, T. and Selleri, L. (2018) Face morphogenesis is promoted by Pbx-dependent EMT via regulation of Snail1 during frontonasal prominence fusion.Development 145, dev157628, doi:10.1242/dev.157628.

Dong, X., Landford, W.N., Hart, J., Risolino, M., Kaymakcalan, O., Jin, J., Toyoda, Y., Ferretti, E., Selleri, L., and Spector, J.A. (2017). Towards Microsurgical Correction of Cleft Lip Ex Utero via Restoration of Craniofacial Developmental ProgramsPlastic and Reconstructive Surgery 144, 75-85,doi:10.1097/PRS.0000000000003417.

Golonzhka, O., Nord, A., Tang, P.L.F., Lindtner, S., Ypsilanti, A.R., Ferretti, E., Visel, A., Selleri, L. and Rubenstein, J.L.R. (2015). Pbx Regulates Patterning of the Cerebral Cortex in Progenitors and Postmitotic Neurons. Neuron 88, 1192-1207, doi:10.1016/j.neuron.2015.10.045.

Handschuh, K., Feenstra,K., Koss, M., Ferretti, E., Risolino, M., Zewdu, R., Sahai, M.A., Benazet, JD., Peng, X.P., Depew, M., Quintana, L., Sharpe, J., Wang, B., Alcorn, H., Rivi, R., Butcher, S., Manak, J.R., Vaccari, T., Weinstein, H., Anderson, K., Lacy, E., and Selleri, L. (2014). ESCRT-II/Vps25 constrains digit number by endosome-mediated selective modulation of FGF-SHH signaling. Cell Reports 9, 674-687, doi:10.1016/j.celrep.2014.09.019.

Feldhahn, N., Ferretti, E., Robbiani, D.F., Callen, E., Deroubaix, S., Selleri, L., Nussenzweig, A., Nussenzweig, M.C. (2012) The hSSB1-orthologue Obfc2b is essential for skeletogenesis but dispensable for the DNA damage response in vivo. EMBO Journal 31, 4045-4056, doi: 10.1038/emboj.2012.247.

Sgadò, P., Ferretti, E., Grbec, D., Bozzi, Y., Simon, H.H. (2012) The atypical homeoprotein Pbx1a participates in the axonal pathfinding of mesencephalic dopaminergic neurons. Neural Development 7, 24, doi:10.1186/1749-8104-7-24.

Ferretti, E., Li, B., Zewdu, R., Wells, V., Hebert, J.M., Karner, C., Anderson, M.J., Williams, T., Dixon, J., Dixon, M., Depew, M.J. and Selleri, L. (2011) A conserved Pbx-Wnt-p63-Irf6 regulatory module controls face morphogenesis by promoting epithelial apoptosis. Developmental Cell 21, 627-641, 10.1016/j.devcel.2011.08.005.

Ferretti, E., Vitobello, A., Lampe, X., Vilain, N., Ducret, S., Ori, M., Spetz, J.F., Selleri, L. and Rijli, F.M. (2011) Hox and Pbx factors control retinoic acid synthesis during hindbrain segmentation. Developmental Cell 20, 469-482, doi: 1016/j.devcel.2011.03.011.

Capellini, T.D., Handschuh, K., Quintana, L., Ferretti, E., Di Giacomo, G., Fantini, S., Vaccari, G., Clarke, S.L., Wenger, A.M., Bejerano, G., Sharpe, J., Zappavigna, V. and Selleri, L. (2011) Control of pelvic girdle development by genes of the Pbx family and Emx2. Developmental Dynamics 240, 1173-1189, doi: 1002/dvdy.22617.

Domyan, E.T., Ferretti, E., Throckmorton, K., Mishina, Y., Nicolis, S.K. and Sun, X. (2011) Signaling through BMP receptors promotes respiratory identity in the foregut via repression of Sox2. Development 138, 971-978, doi:10.1242/dev.053694.

Capellini, T.D., Vaccari, G., Ferretti, E., Fantini, S., He, M., Pellegrini, M., Quintana, L., Di Giacomo, G., Sharpe, J., Selleri, L. and Zappavigna, V.(2010) Scapula development is governed by genetic interactions of Pbx1 with its family members and with Emx2 via their cooperative control of Alx1. Development 137, 2559-2569, doi:10.1242/dev.048819.

Villaescusa, J.C., Buratti, C., Penkov, D., Mathiasen, L., Planagumà J., Ferretti E. and Blasi F. (2009) Cytoplasmic Prep1 interacts with 4EHP inhibiting Hoxb4 translation. PLoS One 4:4, doi:10.1371/journal.pone.0005213.

Di Rosa, P., Villaescusa, J.C., Longobardi, E., Iotti, G., Ferretti, E., Diaz, V.M., Micco, A., Ferrari, G. and Blasi F. (2007) The homeodomaintranscription factor Prep1 (pKnox1) is required for hematopoietic stem and progenitor cell activity. Developmental Biology 311, 324-334, doi:10.1016/j.ydbio.2007.08.031.

Tumpel, S., Cambronero, F., Ferretti E., Blasi, F., Wiedemann, L.M. and Krumlauf R. (2007) Expression of Hoxa2 in rhombomere 4 is regulated by a conserved cross-regulatory mechanism dependent upon Hoxb1. Developmental Biology 302, 646-660, doi:10.1016/j.ydbio.2006.10.029.

Capellini, T.D., Di Giacomo, G., Salsi, V., Brendolan, A., Ferretti, E., Srivastava, D., Zappavigna, V. and Selleri L. (2006). Pbx1/Pbx2 requirement for distal limb patterning is mediated by the hierarchical control of Hox gene spatial distribution and Shh expression. Development 133, 2263-2273, doi:10.1242/dev.02395.

Ferretti, E., Villaescusa, J.C., Di Rosa, P., Fernandez-Diaz, L.C., Longobardi, E., Mazzieri, R., Miccio, A., Micali, N., Selleri, L., Ferrari, G. and Blasi F. (2006). Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype. Molecular and Cellular Biology 26, 5650-5662, doi:10.1128/MCB.00313-06.

Brendolan, A., Ferretti, E., Salsi, V., Moses, K., Quaggin, S., Cleary., M.L. and Selleri, L. (2005). A Pbx1-dependent genetic and transcriptional network regulates spleen ontogeny. Development 132, 3113-3126, doi: 1242/dev.01884.

Ferretti, E., Tumpfel, S., Cambronero, F., Longobardi, E., Wiedemann, L., Blasi, F. and Krumlauf, R. (2005). Hoxb1 enhancer and control ofrhombomere 4 expression: complex interplay between Prep-Pbx1-Hoxb1. Molecular and Cellular Biology 25, 8541-8552, doi:10.1128/MCB.25.19.8541-8552.2005.

Penkov, D., Di Rosa, P., Fernandez Diaz, L., Basso, V., Ferretti, E., Grassi, F., Mondino, A. and Blasi F. (2005) Involvement of Prep1 in thealphabeta T-cell receptor T-lymphocytic potential of hematopoietic precursors. Molecular and Cellular Biology 25, 10768-10781, doi: 1128/MCB.25.24.10768-10781.2005.

Villaescusa, J.C., Verrotti, A.C., Ferretti, E., Farookhi, R. and Blasi, F. (2003). Expression of Hox-cofactor genes during mouse ovarian follicular development and oocyte maturation. Gene 330C, 1-7, doi: 1016/j.gene.2004.01.024.

Deflorian, G., Tiso, N., Ferretti, E., Blasi, F., Bortolussi, M. and Argenton, F. (2003). 1 has unique and essential genetic functions in hindbrain development and neural crest cells differentiation. Development 131, 613-627, doi:10.1242/dev.00948.

Fognani, C., Kilstrup-Nielsen, C., Berthelsen, J., Ferretti, E., Zappavigna, V. and Blasi F. (2002). Characterization of PREP2, a paralog of PREP1, which defines a novel sub-family of the MEINOX TALE homeodomain transcription factors. Nucleic Acids Research 30, 2043-2051.

Manzanares, M., Bel-Vialar, S., Ariza-McNaughton, L., Ferretti, E., Marshall, H., Maconochie, M., Blasi, F. and Krumlauf, R. (2001). Independent regulation of initiation and maintenance phases of HoxA3 expression in the vertebrate hindbrain involve auto and cross-regulatory mechanisms. Development 128, 3595-3607.

Ferretti, E., Marshall, H., Popperl, E., Maconochie, M., Krumlauf, R. and Blasi, F. (2000). Segmental expression of Hoxb2 in r4 requires two separate sites that integrate cooperative interaction between Prep1, Pbx and Hox proteins. Development 127, 155-166.

Ferretti, E., Schulz, H., Talarico, D., Blasi, F. and Berthelsen, J. (1999). The Pbx Regulating Protein Prep-1 is present in a Pbx-complexed form throughout the mouse embryogenesis. Mechanisms of Development 83, 53-64, doi:10.1016/S0925-4773(99)00031-3.

Berthelsen, J., Zappavigna, V., Ferretti, E., Mavilio, F. and Blasi, F. (1998). The novel homeoprotein Prep1 modulates Pbx-Hox protein co-operativity. EMBO Journal 17, 1434-1445, doi:10.1093/emboj/17.5.1434.

Berthelsen, J., Viggiano, L., Schulz, H., Ferretti, E., Consalez, G., Rocchi, M. and Blasi, F. (1998). PKNOX, a Gene Encoding PREP1, a New Regulator of Activity, Maps on Human Chromosome 21q22.3 and Murine Chromosome 17/C. Genomics 47, 323-324, doi:10.1006/geno.1997.5086.