List of publications

Andersen, M.S., Hannezo, E., Ulyanchenko, S., Estrach, S., Antoku, Y., Pisano, S., Boonekamp, K.E., Sendrup, S., Maimets, M., Pedersen M.T., Johansen, J.V., Clement, D.L., Feral, C.C., Simons, B.D., Jensen, K.B. (2019). Tracing the cellular dynamics of sebaceous gland development in normal and perturbed states.Nature Cell Biology, doi: 10.1038/s41556-019-0362-x.

Clevers, H., Conder, R.K., Li, V.S.W., Lutolf, M.P., Vallier, L., Chan, S., Grikscheit, T.C., Jensen, K.B., De Coppi, P. (2019) Tissue-Engineering the intestine: The Trials before the Trials. Cell Stem Cell, 24, 855-859, doi: 10.1016/j.stem.2019.04.018.

Guiu, J., Hannezo, E., Yui, S., Demharter, S., Ulyanchenko, S., Maimets, M., Jørgensen, A., Perlman, S., Lundvall, L., Mamsen, L.S., Larsen, A., Olesen, R.H., Andersen, C.Y., Thuesen, L.L., Hare, K.J., Pers, T.H., Khodosevich, K., Simons, B.D., Jensen, K.B. (2019). Tracing the origin of adult intestinal stem cells. Nature, doi: 10.1038/s41586-019-1212-5.

Chen, X., Cai, G., Liu, C., Zhao, J., Gu, C., Wu, L., Hamilton, T.A., Zhang, C.J., Ko, J., Zhu, L., Qin, J., Vidimos, A., Koyfman, S., Gastman, B.R., Jensen, K.B. and Li, X. (2019). IL-17R-EGFR axis links wound healing to tumorigenesis in Lrig1+ stem cells. Journal of Experimental Medicine 216, 195-214, doi: 10.1084/jem.20171849.

Schweiger, P.J., Clement, D.L., Page, M.E., Schepeler, T., Zou, X., Sirokmány, G., Watt, F.M., and Jensen K.B. (2018). Lrig1 marks a population of gastric epithelial cells capable of long-term tissue maintenance and growth in vitro. Scientific Reports 8, doi: 10.1038/s41598-018-33578-6.

Petersen, N., Frimurer, T.M., Terndrup Pedersen, M., Egerod, K.L., Wewer Albrechtsen, N.J., Holst, J.J., Grapin-Botton, A., Jensen, K.B., and Schwartz, T.W. (2018). Inhibiting RHOA Signaling in Mice Increases Glucose Tolerance and Numbers of Enteroendocrine and Other Secretory Cells in the Intestine. Gastroenterology 155, 1164-1176.e1162, doi:10.1053/j.gastro.2018.06.039.

Moestrup, K.S., Chen, Y., Schepeler, T., Schweiger, P.J., and Jensen, K.B. (2018). Dietary Control of Skin Lipid Composition and Microbiome. Journal of Investigational Dermatology 138, 1225-1228, doi:10.1016/j.jid.2017.12.005.

Holmberg, F.E.O., Pedersen, J., Jorgensen, P., Soendergaard, C., Jensen, K.B., and Nielsen, O.H. (2018). Intestinal barrier integrity and inflammatory bowel disease: Stem cell-based approaches to regenerate the barrier. Journal of Tissue Engineering & Regenerative Medicine 12, 923-935, doi:10.1002/term.2506.

Boyd, M., Thodberg, M., Vitezic, M., Bornholdt, J., Vitting-Seerup, K., Chen, Y., Coskun, M., Li, Y., Lo, B.Z.S., Klausen, P., Jan Schweiger, P., Pedersen, A.G., Rapin, N., Skovgaard, K., Dahlgaard, K., Andersson, R., Terkelsen, T.B., Lilje, B., Troelsen, J.T., Petersen, A.M., Jensen, K.B., Gogenur, I., Thielsen, P., Seidelin, J.B., Nielsen, O.H., Bjerrum, J.T., and Sandelin, A. (2018). Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies. Nature Communications 9, 1661, doi:10.1038/s41467-018-03766-z.

Yui, S., Azzolin, L., Maimets, M., Pedersen, M.T., Fordham, R.P., Hansen, S.L., Larsen, H.L., Guiu, J., Alves, M.R.P., Rundsten, C.F., Johansen, J.V., Li, Y., Madsen, C.D., Nakamura, T., Watanabe, M., Nielsen, O.H., Schweiger, P.J., Piccolo, S., and Jensen, K.B. (2018). YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration. Cell Stem Cell 22, 35-49.e37, doi:10.1016/j.stem.2017.11.001.

Sampaziotis, F., Justin, A.W., Tysoe, O.C., Sawiak, S., Godfrey, E.M., Upponi, S.S., Gieseck, R.L., 3rd, de Brito, M.C., Berntsen, N.L., Gomez-Vazquez, M.J., Ortmann, D., Yiangou, L., Ross, A., Bargehr, J., Bertero, A., Zonneveld, M.C.F., Pedersen, M.T., Pawlowski, M., Valestrand, L., Madrigal, P., Georgakopoulos, N., Pirmadjid, N., Skeldon, G.M., Casey, J., Shu, W., Materek, P.M., Snijders, K.E., Brown, S.E., Rimland, C.A., Simonic, I., Davies, S.E., Jensen, K.B., Zilbauer, M., Gelson, W.T.H., Alexander, G.J., Sinha, S., Hannan, N.R.F., Wynn, T.A., Karlsen, T.H., Melum, E., Markaki, A.E., Saeb-Parsy, K., and Vallier, L. (2017). Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids. Nature Medicine 23, 954-963, doi:10.1038/nm.4360.

Callesen, M.M., Arnadottir, S.S., Lyskjaer, I., Orntoft, M.W., Hoyer, S., Dagnaes-Hansen, F., Liu, Y., Li, R., Callesen, H., Rasmussen, M.H., Berthelsen, M.F., Thomsen, M.K., Schweiger, P.J., Jensen, K.B., Laurberg, S., Orntoft, T.F., Elverlov-Jakobsen, J.E., and Andersen, C.L. (2017). A genetically inducible porcine model of intestinal cancer. Molecular Oncology 11, 1616-1629, doi:10.1002/1878-0261.12136.

Perea, D., Guiu, J., Hudry, B., Konstantinidou, C., Milona, A., Hadjieconomou, D., Carroll, T., Hoyer, N., Natarajan, D., Kallijarvi, J., Walker, J.A., Soba, P., Thapar, N., Burns, A.J., Jensen, K.B., and Miguel-Aliaga, I. (2017). Ret receptor tyrosine kinase sustains proliferation and tissue maturation in intestinal epithelia. EMBO Journal 36, 3029-3045, doi:10.15252/embj.201696247.

Pedersen, M.T., and Jensen, K.B. (2017). Cell biology: Unconventional translation in cancer. Nature 541, 471-472, doi:10.1038/nature21115.

Moestrup, K.S., Andersen, M.S., and Jensen, K.B. (2017). Isolation and In Vitro Characterization of Epidermal Stem Cells. Methods in Molecular Biology 1553, 67-83, doi:10.1007/978-1-4939-6756-8_6.

Dombernowsky, S.L., Schwarz, J., Samsoe-Petersen, J., Albrechtsen, R., Jensen, K.B., Thomas, G., and Kveiborg, M. (2017). Loss of PACS-2 delays regeneration in DSS-induced colitis but does not affect the Apc(Min) model of colorectal cancer. Oncotarget 8, 108303-108315, doi:10.18632/oncotarget.22661.

Andersen, M.S., and Jensen, K.B. (2016). Stem cell heterogeneity revealed. Nature Cell Biology 18, 587-589, doi:10.1038/ncb3368.

Ulyanchenko, S., and Jensen, K.B. (2016). Bimodal skin progenitors-a matter of place and time. EMBO Journal 35, 2628-2630, doi:10.15252/embj.201695880.

Schweiger, P.J., and Jensen, K.B. (2016). Modeling human disease using organotypic cultures. Current Opinions in Cell Biology 43, 22-29, doi:10.1016/j.ceb.2016.07.003.

Le Bouteiller, M., and Jensen, K.B. (2015). Hippo signalling directs intestinal fate. Nature Cell Biology 17, 5-6, doi: 1038/ncb3086.

Guiu, J., and Jensen, K.B. (2015). From Definitive Endoderm to Gut-a Process of Growth and Maturation. Stem Cells & Development 24, 1972-1983, doi:10.1089/scd.2015.0017.

Schepeler, T., Page, M.E., and Jensen, K.B. (2014). Heterogeneity and plasticity of epidermal stem cells. Development 141, 2559-2567, doi:10.1242/dev.104588.

Hannan, N.R., Fordham, R.P., Syed, Y.A., Moignard, V., Berry, A., Bautista, R., Hanley, N.A., Jensen, K.B., and Vallier, L. (2013). Generation of multipotent foregut stem cells from human pluripotent stem cells. Stem Cell Reports 1, 293-306, doi:10.1016/j.stemcr.2013.09.003.

Lu, L., Teixeira, V.H., Yuan, Z., Graham, T.A., Endesfelder, D., Kolluri, K., Al-Juffali, N., Hamilton, N., Nicholson, A.G., Falzon, M., Kschischo, M., Swanton, C., Wright, N.A., Carroll, B., Watt, F.M., George, J.P., Jensen, K.B., Giangreco, A., and Janes, S.M. (2013). LRIG1 regulates cadherin-dependent contact inhibition directing epithelial homeostasis and pre-invasive squamous cell carcinoma development. Journal of Pathology 229, 608-620, doi:10.1002/path.4148.

Page, M.E., Lombard, P., Ng, F., Gottgens, B., and Jensen, K.B. (2013). The epidermis comprises autonomous compartments maintained by distinct stem cell populations. Cell Stem Cell 13, 471-482, doi:10.1016/j.stem.2013.07.010.

Schweiger, P.J., and Jensen, K.B. (2013). Biological techniques: An embryonic view of tumour development. Nature 501, 171-172, doi:10.1038/nature12547.

Fordham, R.P., Yui, S., Hannan, N.R., Soendergaard, C., Madgwick, A., Schweiger, P.J., Nielsen, O.H., Vallier, L., Pedersen, R.A., Nakamura, T., Watanabe, M., and Jensen, K.B. (2013). Transplantation of expanded fetal intestinal progenitors contributes to colon regeneration after injury. Cell Stem Cell 13, 734-744, doi:10.1016/j.stem.2013.09.015.

Tan, D.W., Jensen, K.B., Trotter, M.W., Connelly, J.T., Broad, S., and Watt, F.M. (2013). Single-cell gene expression profiling reveals functional heterogeneity of undifferentiated human epidermal cells. Development 140, 1433-1444, doi:10.1242/dev.087551.

Wong, V.W., Stange, D.E., Page, M.E., Buczacki, S., Wabik, A., Itami, S., van de Wetering, M., Poulsom, R., Wright, N.A., Trotter, M.W., Watt, F.M., Winton, D.J., Clevers, H., and Jensen, K.B. (2012). Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling. Nature Cell Biology 14, 401-408, doi:10.1038/ncb2464.

Wong, V.W., and Jensen, K.B. (2012). Environmental stimuli and intestinal stem cell behavior. Cell Cycle 11, 2767-2768, doi:10.4161/cc.21256.

Fordham, R.P., and Jensen, K.B. (2012). Reporting live from the epidermal stem cell compartment! Cell Stem Cell 11, 141-142, doi:10.1016/j.stem.2012.07.008.

Collins, C.A., Jensen, K.B., MacRae, E.J., Mansfield, W., and Watt, F.M. (2012). Polyclonal origin and hair induction ability of dermal papillae in neonatal and adult mouse back skin. Developmental Biology 366, 290-297, doi:10.1016/j.ydbio.2012.03.016.

Hunziker, L., Benitah, S.A., Braun, K.M., Jensen, K., McNulty, K., Butler, C., Potton, E., Nye, E., Boyd, R., Laurent, G., Glogauer, M., Wright, N.A., Watt, F.M., and Janes, S.M. (2011). Rac1 deletion causes thymic atrophy. Plos One 6, e19292, doi:10.1371/journal.pone.0019292.

Jensen, K.B., Driskell, R.R., and Watt, F.M. (2010). Assaying proliferation and differentiation capacity of stem cells using disaggregated adult mouse epidermis. Nature Protocols 5, 898-911, doi:10.1038/nprot.2010.39.

Baker, C.M., Verstuyf, A., Jensen, K.B., and Watt, F.M. (2010). Differential sensitivity of epidermal cell subpopulations to beta-catenin-induced ectopic hair follicle formation. Developmental Biology 343, 40-50, doi:10.1016/j.ydbio.2010.04.005.

Driskell, R.R., Giangreco, A., Jensen, K.B., Mulder, K.W., and Watt, F.M. (2009). Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis. Development 136, 2815-2823, doi:10.1242/dev.038620.

Watt, F.M., and Jensen, K.B. (2009). Epidermal stem cell diversity and quiescence. EMBO Molecular Medicine 1, 260-267, doi:10.1002/emmm.200900033.

Sorensen, M.D., Gonzalez Dosal, R., Jensen, K.B., Christensen, B., Kolvraa, S., Jensen, U.B., and Kristensen, P. (2009). Epsilon haemoglobin specific antibodies with applications in noninvasive prenatal diagnosis. Journal of Biomedical Biotechnolechnology 2009, 659219, doi:10.1155/2009/659219.

Jensen, K.B., Collins, C.A., Nascimento, E., Tan, D.W., Frye, M., Itami, S., and Watt, F.M. (2009). Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis. Cell Stem Cell 4, 427-439, doi:10.1016/j.stem.2009.04.014.

Giangreco, A., Jensen, K.B., Takai, Y., Miyoshi, J., and Watt, F.M. (2009). Necl2 regulates epidermal adhesion and wound repair. Development 136, 3505-3514, doi:10.1242/dev.038232.

Larsen, M., Jensen, K.B., Christensen, P.A., Suarez, E., Paris, D., Sanz, L., Ravn, P., Sauce, D., Saas, P., Goletz, S., Alvarez-Vallina, L., and Kristensen, P. (2008). Functionally fused antibodies--a novel adjuvant fusion system. Journal of Immunological Methods 339, 220-227, doi:10.1016/j.jim.2008.09.015.

Jensen, K.B., Jones, J., and Watt, F.M. (2008). A stem cell gene expression profile of human squamous cell carcinomas. Cancer Letters 272, 23-31, doi:10.1016/j.canlet.2008.06.014.

Jensen, K.B., and Watt, F.M. (2006). Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescence. Proceedings of the National Academy of Sciences USA 103, 11958-11963, doi:10.1073/pnas.0601886103.

Cuesta, A.M., Suarez, E., Larsen, M., Jensen, K.B., Sanz, L., Compte, M., Kristensen, P., and Alvarez-Vallina, L. (2006). Enhancement of DNA vaccine potency through linkage of antigen to filamentous bacteriophage coat protein III domain I. Immunology 117, 502-506, doi:10.1111/j.1365-2567.2006.02325.x.

Jensen, K.B., and Kristensen, P. (2005). Isolation of recombinant phage-displayed antibodies recognizing skin keratinocytes. Methods in Molecular Biology 289, 359-370.

Jensen, K.B., Jensen, O.N., Ravn, P., Clark, B.F., and Kristensen, P. (2003). Identification of keratinocyte-specific markers using phage display and mass spectrometry. Molecular Cell Proteomics 2, 61-69, doi:10.1074/mcp.M200049-MCP200.

Jensen, K.B., Larsen, M., Pedersen, J.S., Christensen, P.A., Alvarez-Vallina, L., Goletz, S., Clark, B.F., and Kristensen, P. (2002). Functional improvement of antibody fragments using a novel phage coat protein III fusion system. Biochemical and Biophysical Research Communications 298, 566-573, doi:10.1016/S0006-291X(02)02484-1.

Stausbol-Gron, B., Jensen, K.B., Jensen, K.H., Jensen, M.O., and Clark, B.F. (2001). De novo identification of cell-type specific antibody-antigen pairs by phage display subtraction. Isolation of a human single chain antibody fragment against human keratin 14. FEBS Journal 268, 3099-3107, doi:10.1046/j.1432-1327.2001.02210.x.

Ravn, P., Kjaer, S., Jensen, K.H., Wind, T., Jensen, K.B., Kristensen, P., Brosh, R.M., Orren, D.K., Bohr, V.A., and Clark, B.F. (2000). Identification of phage antibodies toward the Werner protein by selection on Western blots. Electrophoresis 21, 509-516, doi:10.1002/(sici)1522-2683(20000201)21:3<509::aid-elps509>3.0.co;2-5.

Kristensen, P., Ravn, P., Jensen, K.B., and Jensen, K. (2000). Applying phage display technology in aging research. Biogerontology 1, 67-78.