List of publications

Thestrup, M.I., Caviglia, S., Cayuso, J., Heyne, R. L. S., Ahmad, R., Hofmeister, W., Satriano, L., Wilkinson, D. G., Andersen, J. B., and Ober, E. A. (2019) A morphogenetic EphB/EphrinB code controls hepatopancreatic duct formation. Nature Communications 10, 5220. doi: 10.1038/s41467-019-13149-7

Caviglia, S. and Ober, E. (2018). Non-conventional protrusions: the diversity of cell interactions at short and long distance.Current Opinion in Cell Biology 54, 106-113, doi: 10.1016/

Ober, E.A. and Lemaigre, F.P. (2018). Development of the liver: insights into organ and tissue morphogenesisJournal of Hepatology 68, 1049-1062, doi:10.1016/j.jhep.2018.01.005.

Lonowski, L.A., Narimatsu, Y., Riaz, A., Delay, C.E., Yang, Z., Niola, F., Duda, K., Ober, E.A., Clausen, H., Wandall, H., Hansen, S.H., Bennett, E.P., and Frödin, M. (2017). Genome editing using FACS enrichment of nuclease-expressing cells and indel detection by amplicon analysis. Nature Protocols 12, 581-603, doi:10.1038/nprot.2016.165.

Wang, S., Miller, S.R., Ober, E.A. and Sadler, K.C. (2017). Making it new again: Insight into liver development, regeneration, and disease from zebrafish research. Current Topics in Developmental Biology 124, 161-195, doi:10.1016/bs.ctdb.2016.11.012.

Cayuso, J., Dzementsei, A., Fischer, J.C., Karemore, G., Caviglia, S., Bartholdson, J., Wright, G.J. and Ober E.A. (2016). EphrinB1/EphB3b Coordinate Bidirectional Epithelial-Mesenchymal Interactions Controlling Liver Morphogenesis and Laterality. Developmental Cell 39, 316-328, doi:10.1016/j.devcel.2016.10.009. Recommended by the faculty of 1000.

Koltowska, K., Lagendijk, A.K., Pichol-Thievend, C., Fischer, J.C., Francois, M., Ober, E.A, Yap, A.S. and Hogan, B.M. (2015). Vegfc Regulates Bipotential Precursor Division and Prox1 Expression to Promote Lymphatic Identity in Zebrafish. Cell Reports 13, 1828-1841, doi:10.1016/j.celrep.2015.10.055.

Ober, E.A. and Grapin-Botton, A. (2015). At new heights - endodermal lineages in development and disease. Development 142, 1912-1917, doi:10.1242/dev.121095.

Dunworth, W.P., Cardona-Costa, J., Bozkulak, E.C., Kim, J.-D., Meadows, S., Fischer, J.C., Wang, Y., Cleaver, O., Qyang, Y., Ober, E.A., and Jin, S.-W. (2014). Bone Morphogenetic Protein 2 Signaling Negatively Modulates Lymphatic Development in Vertebrate Embryos. Circulation Research 114, 56-66, doi:10.1161/circresaha.114.302452.

van Impel, A., Zhao, Z., Hermkens, D.M., Roukens, M.G., Fischer, J.C., Peterson-Maduro, J., Duckers, H., Ober, E.A., Ingham, P.W. and Schulte-Merker, S. (2014). Divergence of zebrafish and mouse lymphatic cell fate specification pathways. Development 141, 1228-U1101, doi:10.1242/dev.105031.

Markmiller, S., Cloonan, N., Lardelli, R.M., Doggett, K., Keightley, M.C., Boglev, Y., Trotter, A.J., Ng, A.Y., Wilkins, S.J., Verkade, H., Ober, E.A., Field, H.A., Grimmond, S.M., Lieschke, G.J., Stainier, D.Y., Heath, J.K. (2014). Minor class splicing shapes the zebrafish transcriptome during development. Proceedings of the National Academy of Sciences of the United States of America 111, 3062-3067, doi:10.1073/pnas.1305536111.

Boglev, Y., Badrock, A.P., Trotter, A.J., Du, Q., Richardson, E.J., Parslow, A.C., Markmiller, S.J., Hall, N.E., de Jong-Curtain, T.A., Ng, A.Y., Verkade, H., Ober, E.A., Field, H.A., Shin, D., Shin, C.H., Hannan, K.M., Hannan, R.D., Pearson, R.B., Kim, S.H., Ess, K.C., Lieschke, G.J., Stainier, D.Y. and Heath, J.K. (2013). Autophagy Induction Is a Tor- and Tp53-Independent Cell Survival Response in a Zebrafish Model of Disrupted Ribosome Biogenesis. Plos Genetics 9, doi:10.1371/journal.pgen.1003279.

Koltowska, K., Apitz, H., Stamataki, D., Hirst, E.M.A., Verkade, H., Salecker, I. and Ober, E.A. (2013). Ssrp1a controls organogenesis by promoting cell cycle progression and RNA synthesis. Development 140, 1912-1918, doi:10.1242/dev.093583.

Schaub, M., Nussbaum, J., Verkade, H., Ober, E.A., Stainier, D.Y.R. and Sakaguchi, T.F. (2012). Mutation of zebrafish Snapc4 is associated with loss of the intrahepatic biliary network. Developmental Biology 363, 128-137, doi:10.1016/j.ydbio.2011.12.025.

Poulain, M. and Ober, E.A. (2011). Interplay between Wnt2 and Wnt2bb controls multiple steps of early foregut-derived organ development. Development 138, 3557-3568, doi:10.1242/dev.055921.

Mas, J. C., E. S. Noel & A. Ober (2011). Chromatin Modification in Zebrafish Development. Zebrafish: Genetics, Genomics and Informatics, 3rd Edition. H. W. Detrich, M. Westerfield and L. I. Zon. San Diego, Elsevier Academic Press Inc. 104, 401-428.

Curado, S., Ober, E.A., Walsh, S., Cortes-Hernandez, P., Verkade, H., Koehler, C.M. and Stainier, D.Y.R. (2010). The mitochondrial import gene tomm22 is specifically required for hepatocyte survival and provides a liver regeneration model. Disease Models & Mechanisms 3, 486-495, doi:10.1242/dmm.004390.

Noël, E.S., dos Reis, M., Arain, Z. and Ober, E.A. (2010). Analysis of the Albumin/alpha-Fetoprotein/Afamin/Group specific component gene family in the context of zebrafish liver differentiation. Gene Expression Patterns 10, 237-243, doi:10.1016/j.gep.2010.05.002.

Munson, C., Huisken, J., Bit-Avragim, N., Kuo, T., Dong, P.D., Ober, E.A., Verkade, H., Abdelilah-Seyfried, S. and Stainier, D.Y.R. (2008). Regulation of neurocoel morphogenesis by Pard6 gamma b. Developmental Biology 324, 41-54, doi:10.1016/j.ydbio.2008.08.033.

Noël, Emily S., Antonio Casal-Sueiro, Elisabeth Busch-Nentwich, Heather Verkade, P. Duc Si Dong, Derek L. Stemple & Elke A. Ober (2008). Organ-specific requirements for Hdac1 in liver and pancreas formation. Developmental Biology 322, 237-250, doi:10.1016/j.ydbio.2008.06.040. 

Osborne, N., Brand-Arzamendi, K., Ober, E.A., Jin, S.-W., Verkade, H., Holtzman, N.G., Yelon, D. and Stainier, D.Y.R. (2008). The Spinster Homolog, Two of Hearts, Is Required for Sphingosine 1-Phosphate Signaling in Zebrafish. Current Biology 18, 1882-1888, doi:10.1016/j.cub.2008.10.061.

Shin, C.H., Chung, W.-S., Hong, S.-K., Ober, E.A., Verkade, H., Field, H.A., Huisken, J. and Stainier, D.Y.R. (2008). Multiple roles for Med12 in vertebrate endoderm development. Developmental Biology 317, 467-479, doi:10.1016/j.ydbio.2008.02.031.

Shin, D., Shin, C.H., Tucker, J., Ober, E.A., Rentzsch, F., Poss, K.D., Hammerschmidt, M., Mullins, M.C. and Stainier, D.Y.R. (2007). Bmp and Fgf signaling are essential for liver specification in zebrafish. Development 134, 2041-2050, doi: 10.1242/dev.000281.

Geisler, R., Rauch, G.J, Geiger-Rudolph, S., Albrecht, A., van Bebber, F., Berger, A., Busch-Nentwich, E., Dahm, R., Dekens, M.P., Dooley, C., Elli, A.F., Gehring, I., Geiger, H., Geisler, M., Glaser, S., Holley, S., M., Kerr, A., Kirn, A., Knirsch, M., Konantz, M., Küchler, A.M., Maderspacher, F., Neuhauss, S.C., Nicolson, T., Ober, E.A., Praeg, E., Ray, R., Rentzsch, B., Rick, J.M., Rief, E., Schauerte, H.E., Schepp, C.P., Schönberger, U., Schonthaler, H.B., Seiler, C., Sidi, S., Söllner, C., Wehner, A., Weiler, C. and Nüsslein-Volhard, C. (2007). Large-scale mapping of mutations affecting zebrafish development. Bmc Genomics 89, doi:10.1186/1471-2164-8-11.

Jin, S.W., Herzog, W., Santoro, M.M., Mitchell, T.S., Frantsve, J., Jungblut, B., Beis, D., Scott, I.C., D'Amico, L.A., Ober, E.A., Verkade, H., Field, H.A., Chi, N.C., Wehman, A.M., Baier, H. and Stainier, D.Y. (2007). A transgene-assisted genetic screen identifies essential regulators of vascular development in vertebrate embryos. Developmental Biology 307, 29-42, doi:10.1016/j.ydbio.2007.03.526.

Ober, E.A., Verkade, H., Field, H.A. and Stainier, D.Y.R. (2006). Mesodermal Wnt2b signalling positively regulates liver specification. Nature 442, 688-691, doi:10.1038/nature04888.

Beis, D., Bartman, T., Jin, S.-W., Scott, I.C., D'Amico, L.A., Ober, E.A., Verkade, H., Frantsve, J., Field, H.A., Wehman, A., Baier, H., Tallafuss, A., Bally-Cuif, L., Chen, J.-N., Stainier, D.Y.R. and Jungblut, B. (2005). Genetic and cellular analyses of zebrafish atrioventricular cushion and valve development. Development 132, 4193-4204, doi:10.1242/dev.01970.

Ober, E.A., Olofsson, B., Mäkinen, T., Jin, S.-W., Shoji, W., Koh, G.Y., Alitalo, K. and Stainier, D.Y.R. (2004). Vegfc is required for vascular development and endoderm morphogenesis in zebrafish. Embo Reports 5, 78-84, doi:10.1038/sj.embor.7400047.

Loosli, F. , Staub, W., Finger-Baier, K., Ober, E.A., Verkade, H., Wittbrodt, J. and Baier, H. (2003). Loss of eyes in zebrafish caused by mutation of chokh/rx3. Embo Reports 4, 894-899, doi:10.1038/sj.embor.embor919.

Field, H.A., Ober, E.A., Roeser, T. and Stainier, D.Y.R. (2003). Formation of the digestive system in zebrafish. I. Liver morphogenesis. Developmental Biology 253, 279-290, doi:10.1016/s0012-1606(02)00017-9.

Ober, E.A., Field, H.A. and Stainier, D.Y.R. (2003). From endoderm formation to liver and pancreas development in zebrafish. Mechanisms of Development 120, 5-18, doi:10.1016/s0925-4773(02)00327-1.

Ober, E.A. & Schulte-Merker, S. (1999). Signals from the yolk cell induce mesoderm, neuroectoderm, the trunk organizer, and the notochord in zebrafish. Developmental Biology 215, 167-181, doi:10.1006/dbio.1999.9455.

Münchberg, S.R., Ober, E.A. and Steinbeisser, H. (1999). Expression of the Ets transcription factors erm and pea3 in early zebrafish development. Mechanisms of Development 88, 233-236, doi:10.1016/s0925-4773(99)00179-3.